Ilana Livyatan

1998 - 2000 B.Sc. in Computer Science and Life Sciences,
The Hebrew University of Jerusalem
2008 - 2010 M.Sc. Studies in Genetics, The Hebrew University of Jerusalem
Supervisor: Prof. Eran Meshorer
2010 - 2016 PhD in Genetics, The Hebrew University of Jerusalem
Supervisor: Prof. Eran Meshorer
Dissertation title: Identification and Characterization of Non-polyadenylated
RNA in Embryonic Stem Cells and Differentiated Cells (2017)
Publications #1,2,3,4,5 (Article list below)
2017 - 2022 Postdoctoral fellow in Department of Molecular Cell Biology and Faculty of
Applied Mathematics and Computer Science, WIS
Hosts: Prof. Ravid Straussman, Prof. Eran Segal
Research interests: Computational analysis of microbiome in health and
cancer disease
Publications: #6, #7

2000 – 2005 Software Developer Check Point Software Technologies Ltd.
• Kernel and driver development in the kernel infrastructure team
o Multi-platform: Linux, Solaris, Windows, HP, IPSO
o Multi-layer networking protocols security enforcement: TCP/IP, IPv6, Ethernet,
VoIP, HTTP, IKE, IPsec
2006 – 2008 Infrastructure Architect Check Point Software Technologies Ltd.
• Design of kernel and user space infrastructure
• Integration between infrastructure and higher level components
• Research management of product performance
o Development of performance-testing and benchmarking tools
o Integration with 3rd party performance testing tools
o Research of product performance on new hardware technologies: Dual Core
Technologies (Intel, AMD, and Sun), network device drivers, PCI/PCI-Express buses
• Technical leader of inter-company relationships to support research efforts
o Focal point for collaboration with Intel
• In house educator - development and delivery of in-house courses covering project
design, coding support tools, and performance analysis
2008 -2016 Research Student in Genetics Lab HUJI
• Webtool and database design and implementation for integrated epigenetic analysis of
ChIP-seq experiments
• Research of the coding and non-coding transcriptional landscape in embryonic stem
cells and differentiated neuronal progenitor cells
o "Big Data" analysis - ChIP-seq, RNA-seq, whole genome tiling arrays
o Proficiency in - C, MATLAB, R, Perl, Mysql, HTML, PHP, Javascript
o Cell culture - embryonic stem cells and cell differentiation
o Molecular methods - PCR, Antisense RT-PCR
o Protein characterization - Western Blotting, ChIP
2017 Scientific Consultant SpliSense
o Off-target analysis for drug candidates targeting major splicing mutations in genetic
diseases
2017 -2022 Postdoctoral fellow Weizmann Institute
• Tumor and gut microbiome / mycobiome
o Cancer biology
o Microbiome analysis of NGS metagenomics and 16S amplification libraries
o Establishment of ITS2 amplification protocol and supporting databases of fungal
sequences for Mycobiome research
o Functional analysis of microbial populations
o Machine learning and advanced data science
o Python expertise
o Student mentoring (undergrad interns, rotation and graduate students)
o Widespread collaboration with both local and international community of
oncologists
o EMBO Laboratory Leadership Course for Postdocs at WIS (2019)
2020 -PRESENT Lecturer Jerusalem College of Technology
Design and lecture of courses:
o Systems Biology
o Advanced biological data mining and analysis
O Machine learning approaches in clinical diagnostics
2022 -PRESENT Research Associate Weizmannn Institute

2013 The AS-ILS Selected Monthly ARTicle (SMART) Prize for publication in Nucleic
Acids Research of "Non-polyadenylated transcription in embryonic stem cells reveals
novel non-coding RNA related to pluripotency and differentiation" (HUJI)
• 2013 Dean's distinction for Excellent Teaching of General Genetics Lab (junior
faculty)
• 2014 Dean's distinction for Excellent Teaching of Fundamentals of Probability and
Statistical Analysis (junior faculty)
• 2015 Muchrik Prize of Excellence for PhD studies (HUJI)
• 2017-2018 Dean of Faculty Postdoctoral Fellowship (WIS)
• 2020 The Azrieli Systems Biology Innovative Award (6th round, WIS)

Mentor of high school student for Research Study Project Matriculation, The Israel
Ministry of Education. Student received final grade of 100 and co-author on paper.
(2014)

• Mentoring of undergraduates in B.Sc Bioinformatics program at Machon Tal
(Jerusalem College of Technology) - 3
rd year final project (2019-2020)
• Rotation students for M.Sc.
o 2018-2019 Arnon Meltser, “Pipeline development for ITS2 sequencing”, cosupervisor: Prof. Ravid Straussman
o 2019-2020 Dan Feigin, “Development of GFlask – Gene set functional level
analysis software kit of bacterial functions”, co-supervisor: Prof. Ravid
Straussman
o 2021 Sara Rosen, “High-level functional analysis of bacteria in human
tumors”, co-supervisor: Prof. Ravid Straussman
• Mentor in WeizMom project at WIS to support women in academia (current)
• WISER mentoring women postdocs

• Member of the organizing committee of the One2many systems biology conference
(2022).
• Established international post-doc peer group to co-train on academic soft skills
(2019)

2008 - 2013 Junior faculty
General Genetics A – Lab (for Bachelor’s)
Design and execution of new drosophila genetics lab
2013 - 2014 Junior faculty
Fundamentals of Probability and Statistical Analysis – Exercise (for Bachelor’s)
Intro to Statistics and Probability -Honor's program – Exercise (for Bachelor’s)

Symbols and abbreviations: Principal Investigator PI, studentS
, post-doctoral fellowPD, coresearcherC
, technicianT
° Impact factor (IF) was calculated as the 2 years average of citations/document based on
data from Scimago institutions rankings (www.scimagojr.com). This is equivalent to the
journal impact factor ™ (Thomson Reuters) metric
* Equal author contributions
Chapters in Collections, Previews:
1. Livyatan I S, Meshorer E PI. SON sheds light on RNA splicing and pluripotency. Nat Cell
Biol. 15, no. 10 (October 2013): 1139–40. IF°: 15.57, Q1
2. Livyatan I S, Meshorer E PI. The HDAC interaction network. Mol Syst Biol. 9 (2013):
671. IF°: 14.029, Q1
3. Livyatan, I S, Meshorer, E PI. Forward and reverse epigenomics in embryonic stem
cells. Handbook of Nutrition, Diet, and Epigenetics. (2017): 2269-2288.
4. Livyatan, I PD, Nejman, D PD, Shental, N. C, Straussman, R PI. Characterization of the
human tumor microbiome reveals tumor-type specific intra-cellular bacteria.
Oncoimmunology 9, no. 1 (July 29, 2020): 1800957. IF°: 7.192, Q1
Articles
1. Livyatan I S
, Harikumar A S
, Nissim-Rafinia M T
, Duttagupta R S
, Gingeras TR C
,
Meshorer E PI. Non-polyadenylated transcription in embryonic stem cells reveals
novel non-coding RNA related to pluripotency and differentiation. Nucleic Acids Res.
41, no. 12 (July 2013): 6300–6315. IF°: 9.646, Q1, Cited: 20
2. Gokhman D S
, Livyatan I S
, Sailaja BS S
, Melcer S S
, Meshorer E PI. Multilayered
chromatin analysis reveals E2f, Smad and Zfx as transcriptional regulators of
histones. Nat Struct Mol Biol. 20, no. 1 (January 2013): 119–26. IF°: 9.408, Q1, Cited:
28
3. Alajem A S
, Biran A S
, Harikumar A S
, Sailaja BS S
, Aaronson Y S
, Livyatan I
S
, NissimRafinia M T
, Sommer AG S
, Mostoslavsky G C
, Gerbasi VR, Golden DE, Datta A, Sze SK,
Meshorer E PI
. Differential association of chromatin proteins identifies
BAF60a/SMARCD1 as a regulator of embryonic stem cell differentiation. Cell Rep. 10,
no. 12 (March 31, 2015): 2019–31. IF°: 7.87, Q1, Cited: 31
4. Livyatan, I S
, Aaronson, Y S
, Gokhman, D S
, Ashkenazi, R S
, Meshorer, E PI. BindDB: an
integrated database and webtool platform for "reverse-ChIP" epigenomic analysis
and the identification of gene family regulators in embryonic stem cells. Cell Stem
Cell. 17, no. 6 (December 3, 2015): 647–48. IF°: 22.387, Q1, Cited: 14
5. Aaronson, Y* S
, Livyatan, I* S
, Gokhman, D S
, Meshorer, E PI. Systematic identification
of gene family regulators in mouse and human embryonic stem cells. Nucleic Acids
Res. 44, no. 9 (May 19, 2016): 4080–89. IF°: 10.162, Q1, Cited: 4
6. Nejman, D* PD
, Livyatan, I*
PD, Fuks, G* S
, Gavert, N T
, Weiser, R S
, Geller, L S
, ... Segal,
E
PI, Sandbank, J C
, Shental, N C
, Straussman, R PI. The human tumor microbiome is
composed of tumor type-specific intra-cellular bacteria. Science 368, no. 6494 (May
29, 2020): 973–80. IF°: 41.845, Q1, Cited: 247
7. Narunsky Haziza, L* S
, Sepich-Poore, GD* S
, Livyatan, I*
PD, Asraf, O S
, Martino, C S
,
Nejman, D T
, Gavert, N T
, Stajich, JE S
, Amit, G S
, Gonzalez, A S
, Wandro, S S
, Perry, G S
,
Ariel, R T
, Meltser, A S
, Shaffer, JP S
, Zhu, Q S
, Balint-Lahat, N C
, Barshak, I C
, Dadiani, M
C
, Gal-Yam, EN C
, Patel, SP C
, Bashan, A C
, Swafford, AD C
, Pilpel, Y PI, Knight, R PI
,
Straussman, R PI. Pan-cancer analyses reveal cancer type-specific fungal ecologies
and bacteriome interactions. Cell 185, no. 19 (September 29, 2022): TBD. IF°: 25.72,
Q1, Cited: NA.
Patents
1. Straussman, R. PI, Shental, N. C
, Livyatan, I. PD, Rosenberg-Nejman, D. PD, Fuks, G. S
Methods of Diagnosing Cancer and Predicting Responsiveness to Therapy. US
provisional patent April 6, 2020. Relates to publication #6. Licensed to Micronoma TM
2. Straussman, R. PI, Pilpel, Y. C
, Narunsky-Haziza, L. S
, Livyatan, I.
PD Tumor Mycobiome
for Diagnosing Cancer. Israeli provisional patent, July 14, 2021.